By Alexandre Alexakis, Norbert Krause, Simon Woodward
This publication displays the expanding curiosity one of the chemical man made group within the zone of uneven copper-catalyzed reactions, and introduces readers to the newest, most important advancements within the field.
The contents are equipped in accordance with response sort and canopy mechanistic and spectroscopic points in addition to purposes within the synthesis of traditional items. an entire bankruptcy is dedicated to realizing how basic organometallics have interaction with copper to supply selective catalysts for allylic substitution and conjugate addition, either one of that are taken care of in separate chapters. one other is dedicated to the diversity of substrates and experimental protocols, whereas a complete bankruptcy covers the use on non-carbon nucleophiles. different chapters take care of less-known reactions, comparable to carbometallation or the additions to imines and similar platforms, whereas the extra tested reactions cyclopropanation and aziridination in addition to using copper (II) Lewis acids are warranted their very own distinct chapters. extra chapters obstacle the approaches concerned, as decided via mechanistic experiences. ultimately, an entire bankruptcy is dedicated to the artificial applications.
this is often crucial studying for researchers at educational associations and pros at pharmaceutical or agrochemical businesses.